La Jolla Pharmaceutical Company has created
a collection of key articles on B cell
tolerance. Summaries of these articles,
written by LJP scientists, are indexed
below.
Summaries of Selected Articles
from the Scientific Literature
By: Andrew Wiseman, Ph.D., Matt Linnik,
Ph.D., Mike Iverson, Ph.D., Mary-Ann
Campbell, Ph.D.
- Elimination
of Self-Reactive B Lymphocytes Proceeds
in Two Stages: Arrested Development
and Cell Death
By Suzanne B. Hartley, Michael P.
Cooke, David A. Fulcher, Alan W. Harris,
Suzanne Cory, Antony Basten, and Christopher
C. Goodnow
- Different
Nuclear Signals are Activated by the
B Cell Receptor during Positive Versus
Negative Signaling
By James I. Healy, Ricardo E. Doimetsch,
Luika A. Timmerman, Jason G. Cyster,
Mathew L. Thomas, Gerald R. Crabtree,
Richard S. Lewis, and Christopher
C. Goodnow
- Whither
the Anergic B-cell
By David A. Fulcher and Antony Basten
- Cross-linking
of Membrane Immunoglobulin D, in the
Absence of T C Help, Kills Mature
B cells in Vivo
By Fred D. Finkelman, Joanne M. Holmes,
Oksana I. Dukhanina, and Suzanne C.
Morris
- Engagement
of the Antigen-Receptor on Immature
Murine B Lymphocytes Results in Death
by Apoptosis
By Amanda Norvell, Laura Mandik and
John B. Monroe
- Self-reactive
B Cells Are Not Eliminated or Inactivated
by Autoantigen Expressed on Thyroid
Epithelial Cells
By Srinivas Akkaraju, Karen Canaan,
and Christopher C. Goodnow
- Autoreactive
B Cell Regulation: Peripheral Induction
of Development Arrest by Lupus-Associated
Autoantigens
By Sandra Santulli-Marotto, Marc W.
Retter, Renelle Gee, Mark J. Mamula,
and Stephen J. Clark
- Receptor
Editing in a Transgenic Mouse Model:
Site, Efficacy, and Role of B Cell
Tolerance and Antibody Diversification
By Roberta Pelanda, Stephen Schwers,
Eiichiro Sonoda, Raul M.Torres, David
Nemazee and Klaus Rajewsky
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